Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year face a higher risk of heart failure compared to those who do not use this common sleep aid.
Study Findings
The study showed that long-term melatonin users were more likely to be diagnosed with heart failure, require hospitalization for the condition, or die from any cause. These findings were presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans.
However, this preliminary research has not yet undergone peer review and does not prove a direct cause-and-effect between melatonin use and heart failure risk.
Researcher Insights and Concerns
“Melatonin supplements may not be as harmless as commonly assumed.”
Researchers emphasized the safety concerns surrounding prolonged melatonin use and called for further studies to evaluate the cardiovascular risks associated with these supplements.
They also pointed out that many melatonin products are available over-the-counter without prescription or regulation, allowing unrestricted use without medical supervision.
Key Points
- Long-term melatonin use linked to increased heart failure risk.
- Study results suggest need for more cardiovascular safety research.
- Most melatonin supplements are unregulated and widely accessible.
Author’s Summary
Extended melatonin supplement use may raise cardiovascular risks, highlighting the need for cautious use and additional research on their long-term safety.