Nanometer-Detail Cell Maps with Native Infrared Spectroscopy
Native Infrared Spectroscopy produces high-resolution molecular maps of live cells and cell organelles.
Infrared vibrational spectroscopy enables the production of high-resolution maps of molecules inside live cells and cell organelles.
A study by Helmholtz-Zentrum Berlin and Humboldt University uses infrared vibrational spectroscopy and scattering-type near-field optical microscopy to create high-resolution molecular maps in their native environment.
Conducting biological studies in dry environments is challenging due to sample fixation and drying disrupting cell behavior.
Analyzing liquid samples requires conditions that can distort cells, compromising morphology and integrity.
Native infrared spectroscopy could enable high-resolution maps of molecules inside live cells and cell organelles.
Author's summary: High-resolution molecular maps of live cells.